0050600
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Epstein-Barr Virus Antibody Panel I

EBV PAN
Example Reports
Detected
Not Detected

Ordering Recommendation

Aids in diagnosis of primary Epstein-Barr virus infectious mononucleosis after a suspected false-negative heterophile antibody (Monospot) test.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transport 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, icteric, or grossly hemolyzed specimens.

Remarks

Label specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

Reference Interval

Test Number
 Components
 Reference Interval
  EBV Antibody to Early (D) Antigen IgG 10.9 U/mL or less
  EBV Antibody to Viral Capsid Antigen IgG 21.9 U/mL or less
  EBV Antibody to Viral Capsid Antigen IgM 43.9 U/mL or less
  EBV Antibody to Nuclear Antigen IgG 21.9 U/mL or less

Interpretive Data




Component Interpretation
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG 17.9 U/mL or less: Not Detected
18.0-21.9 U/mL:  Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM 35.9 U/mL or less: Not Detected
36.0-43.9 U/mL: Indeterminate.   Repeat testing in 10-14 days may be helpful.
44.0 U/mL or greater: Detected
Epstein-Barr Virus Antibody to Nuclear Antigen, IgG 17.9 U/mL or less: Not Detected
18.0-21.9 U/mL: Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG 8.9 U/mL or less: Not Detected
9.0-10.9 U/mL: Indeterminate - Repeat testing in 10-14 days may be helpful.
11.0 U/mL or greater: Detected

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86665 x2; 86664; 86663

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Components

Component Test Code* Component Chart Name LOINC
0050225 EBV Antibody to Early (D) Antigen IgG 50969-5
0050235 EBV Antibody to Viral Capsid Antigen IgG 7885-7
0050240 EBV Antibody to Viral Capsid Antigen IgM 7886-5
0050245 EBV Antibody to Nuclear Antigen IgG 30083-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • EA-D IgG Ab
  • EBNA-IgG Ab
  • EBV Antibodies
  • EBV Antibody Panel I
  • EBV VCA-IgG Ab
  • EBV VCA-IgM Ab
  • Infectious Mononucleosis Antibody Panel
Epstein-Barr Virus Antibody Panel I